
Infectious Disease Billing Services for ID Physician Groups
Infectious disease billing pays when inpatient consults are billed with hospital care codes instead of consult codes, infusion lines follow NCCI, and HIV and sepsis diagnoses are sequenced as the ICD-10-CM guidelines require. This page covers the physician claim for ID groups, from the first inpatient consult to OPAT follow-up.
Standards We Work Under
In short: Medicare does not recognize consult codes, so an ID physician bills 99221 to 99223 on the first visit by the group and 99231 to 99233 after that. OPAT has no code of its own: the visit is an office or home E/M, with infusion lines only when given in the office. B20 stays on the claim once HIV illness is documented.
The Infectious Disease Codes We Bill Most
| Code | Description | Notes |
|---|---|---|
| 99221 to 99223 | Initial hospital inpatient or observation care | Replaces consult codes; AI only for the principal physician of record |
| 99231 to 99233 | Subsequent hospital inpatient or observation care | One per date per physician or same-specialty group |
| 99202 to 99215 | Office or outpatient visits, new and established | Clinic follow-up and OPAT visits |
| 96365 | IV infusion for therapy, first hour | Status A. One initial administration code per encounter; office only for the physician |
| G0316 | Prolonged inpatient or observation evaluation, each 15 minutes | Status A. Thresholds 90 and 65 minutes after 99223 and 99233 |
| G2212 | Prolonged office or outpatient evaluation, each 15 minutes | 99215 plus one unit at 69 to 83 minutes |
| G2211 | Visit complexity add-on for ongoing care | HIV named as an example in the MLN booklet; not paid on a base code with modifier 25 apart from listed exceptions |
| G0181 | Home health care plan oversight | Status A. 30 minutes a month, one unit, billed after month end |
| 36573 | PICC insertion with imaging, age 5 and over | Status A, 000 day global |
| B20 | Human immunodeficiency virus [HIV] disease | ICD-10-CM 2027. Assigned on every encounter once an HIV illness has developed |
| Z21 | Asymptomatic human immunodeficiency virus [HIV] infection status | ICD-10-CM 2027. Never after B20 |
| A41.9 and R65.20 | Sepsis, unspecified organism; severe sepsis without septic shock | ICD-10-CM 2027. R65.2 is never principal |
Modifiers That Matter
| Modifier | Use |
|---|---|
| AI | Principal physician of record on 99221 to 99223. Only one physician per admission, normally the admitting physician and not the ID consultant. |
| FS | Split or shared hospital visit with a nurse practitioner or physician assistant in the same group. Not for office or nursing facility visits. |
| 25 | Significant, separately identifiable E/M on the day of an infusion or procedure. Never with 99211. |
| 59 or X modifiers | Only when NCCI allows a second initial infusion code at a separate IV access site and the record shows it. |
Payer Rules to Know
| Payer | Rule |
|---|---|
| Medicare | No consult codes since January 1, 2010. First visit by the group is 99221 to 99223, later visits 99231 to 99233. G0316 for prolonged hospital time. FS on split or shared visits. |
| UnitedHealthcare | Commercial policy 2026R0129A does not reimburse 99252 to 99255 from October 1, 2019, but considers telehealth consult G-codes and e-consults when the requester is on the claim. |
Top Denials in Infectious Disease Billing Services for Id Physician Groups
| Reason | Why it happens | Our fix |
|---|---|---|
| CO-97 | Payer treats an infusion flush, hydration or a second same-day visit as included in another payment | Remove integral lines under NCCI Chapter XI, fold the work into one visit, and appeal only when separate work is documented |
| CO-4 | Modifier 25, FS or AI is missing or does not fit the code | Add the modifier the note supports and resubmit; never add 25 to 99211 |
| CO-18 | A second member of the same group and specialty billed an initial code for the same stay | Rebill the later visit as a subsequent code, 99231 to 99233 |
| CO-16 | The claim lacks information, such as the requesting physician on a telehealth consult or a home health agency number on G0181 | Add field 17 or 17B data or the agency number and resubmit |
| CO-151 | Payer does not see support for the number of units, such as G0316 without enough minutes or infusion units that exceed the dose | Check total time or dose against the units, correct the claim and appeal with the record |
What Does Infectious Disease Billing Cover?
Infectious disease billing covers the physician claim for inpatient consults, daily hospital rounds, clinic follow-up, antibiotic infusion work and HIV care. Most denials come from how inpatient consults and outpatient parenteral antibiotic therapy (OPAT, IV antibiotics continued after discharge) are coded.
The hospital bills its own claim on the UB-04. The ID group bills on the CMS-1500, mainly with 99223, 99233, 99214 and infusion codes such as 96365 when the group runs an infusion suite.
Shared inpatient rules are on hospitalist billing, ICU time rules on critical care billing, and office E/M basics on internal medicine billing.
Does Medicare Pay Consultation Codes for an Inpatient ID Consult?
No. Chapter 12, section 30.6.10 of the Medicare Claims Processing Manual says that effective January 1, 2010, consultation codes are no longer recognized for Medicare Part B payment. The October 2026 fee schedule file, RVU26D, lists consult code 99253 with status I.
The ID physician bills the most appropriate initial hospital care code (99221 to 99223) or subsequent hospital care code (99231 to 99233). Section 30.6.9.1 says work once reported with a consult code can be billed as an initial hospital care code only when it meets every requirement of that code, which are higher than for consult codes 99251 and 99252.
Section 30.6.10 also lets a subsequent hospital care code be used for a first visit when the record supports the level, and tells MACs not to find fault because it is the physician's first E/M for the stay. A short first visit that falls below 99221 can go out as 99231 or 99232.
How Do You Tell an Initial Visit from a Subsequent Visit for an ID Physician?
An initial service is the first professional service the patient has had during the stay from the physician or another physician of the same specialty in the same group. Chapter 12, section 30.6.9.E calls everything after that subsequent. The test is your group and specialty, not whether the hospitalist already saw the patient.
So a hospitalist, a surgeon and an ID physician can each bill an initial code on one admission (section 30.6.9.1.G). Only the principal physician of record, who oversees care from the other specialists, adds modifier AI, and only one physician per admission holds that role.
The usual loss is the partner visit. If ID sees a patient Monday and a partner in the same group sees the patient Wednesday, Wednesday is subsequent. Sending 99222 because the second doctor is new to the patient invites a CO-18 duplicate or a downcode.
Section 30.6.9 adds a per diem rule: a MAC pays one hospital visit per day for the same patient from the same physician or same-specialty group. Different specialties with different diagnoses are both paid.
How Do We Level an Inpatient ID Consult?
Level by medical decision making (MDM) or by total time on the date. Chapter 12 says a medically appropriate history and exam are still required but no longer pick the level. The AMA sets the MDM table, so our coders level from the current CPT guidelines.
RVU26D lists time labels of 40, 55 and 75 minutes for 99221 to 99223 and 25, 35 and 50 minutes for 99231 to 99233. Only distinct time counts, and when a physician and nurse practitioner meet the patient together, one person's time is counted (section 30.6.18.B).
| Code | What it covers | Fee schedule label (RVU26D) |
|---|---|---|
| 99221 to 99223 | First service during the stay by the physician or same-group specialty | 40, 55 and 75 minutes |
| 99231 to 99233 | Each later service by the same physician or same-group specialty | 25, 35 and 50 minutes |
Write the reasoning in the assessment: the organism, the susceptibility result you relied on, the drug decision, the monitoring it needs, and who you discussed it with.
Can an ID Physician Bill a Split or Shared Visit with a Nurse Practitioner?
Yes, in a facility setting. Section 30.6.18 defines a split or shared visit as an E/M performed partly by a physician and partly by an NPP in the same group, paid to the practitioner who did the substantive portion: more than half the total time or a substantive part of the MDM since 2024.
Append modifier FS. Office and nursing facility visits cannot be billed this way, so the rule helps the inpatient service but not the clinic. Our hospitalist billing page covers FS documentation.
How Do We Bill Prolonged Services for a Complex ID Visit?
For Medicare hospital visits billed by time, use HCPCS G0316, not CPT 99418. RVU26D lists G0316 as status A and 99418 as status I. Section 30.6.15.3 sets the thresholds: 90 minutes of total time on the date after 99223, 65 after 99233 and 110 after 99236.
Prolonged services apply only when time chose the level, and never with emergency department visits or critical care. In the clinic, section 30.6.15.2 says 99215 plus one unit of G2212 needs 69 to 83 minutes of total time, and 99205 plus one unit needs 89 to 103.
An ID physician spends 95 minutes on a patient with bacteremia and an infected valve: chart review, exam, a call with cardiac surgery and an antibiotic plan. Time chose the level, so the Medicare claim carries 99223 and one unit of G0316.
How Do We Bill OPAT Visits and Infusions Given in the Clinic?
OPAT has no code of its own. The ID physician bills the visit E/M that fits the setting, an office code from 99202 to 99215 or a home visit code from 99341 to 99350, plus drug administration only when the group gives the infusion in a non-facility room.
NCCI Policy Manual Chapter XI, section B sets the infusion rules. Only one initial administration code (96360, 96365, 96374) is reported per encounter unless drugs run at separate IV access sites. Hydration with another drug, fluid used only to keep a line open and port flushes are not separately reportable, and 96523 is not reported for them.
Physicians report 96360 to 96379 for office services but not in a facility setting such as a hospital outpatient department, where the hospital reports them. An ID group that sends patients to a hospital infusion center bills the visit only.
The drug administration codes are valued to include 99211, so 99211 is not reportable with them. Codes 99202 to 99205 and 99212 to 99215 can be billed with modifier 25 when the physician provides a significant, separately identifiable E/M. The record has to show work beyond the infusion itself, such as a new fever and a change in the plan.
| Service | Code | Rule to remember |
|---|---|---|
| Visit on infusion day | 99212 to 99215 with 25 | Not 99211; document the separate work |
| Antibiotic infusion, first hour | 96365 | One initial code per encounter; later drugs use add-on codes |
| PICC placement with imaging | 36573 (age 5 and over) | Status A, 000 day global; separately reportable, unlike peripheral IV starts |
| Peripheral IV start | 36000, 36410 | Not reported with infusion codes |
| Antibiotic drug | J0696 ceftriaxone, per 250 mg | Units match the HCPCS descriptor |
For antibiotics, check that the units on the J-code line match the dose given. Discarded drug modifiers are explained on our oncology page.
Can an ID Physician Bill for Managing a Home Infusion Patient Between Visits?
Sometimes. Care plan oversight, HCPCS G0181 (status A), pays for physician supervision of a patient receiving complex care from a Medicare-participating home health agency or hospice. Chapter 12, section 180 requires 30 or more minutes of physician time in the month.
Section 180.1 says the claim carries no other services, is billed only after month end, covers one calendar month and one unit, and carries the agency's provider number. In RVU26D, 99374 is status B and 99375 is status I, so Medicare uses G0181. An OPAT patient not under a home health plan of care has no CPO path.
How Do We Sequence B20 and Z21 for HIV Visits?
Use B20 when the provider documents AIDS, HIV disease or treatment of an HIV-related illness. Use Z21 only when the record says HIV positive or similar and shows no symptoms or HIV-related illness. These rules are in the FY 2027 ICD-10-CM Official Guidelines, section I.C.1.a.2.
Once an HIV-related illness has developed, B20 is assigned on every later encounter, and the patient is never assigned R75 or Z21 afterward. The guidelines also say confirmation does not require positive serology in the note; the provider's statement is enough.
| Documentation | Code | Sequencing |
|---|---|---|
| AIDS, HIV disease, or treated HIV-related illness | B20 | First when the visit is for the HIV condition, then each related condition |
| HIV positive, no symptoms or related illness | Z21 | Only if never B20 |
| Admitted for an unrelated condition such as an injury | Unrelated condition first | B20 secondary |
| Screening with no signs or symptoms | Z11.4 | Add high-risk behavior codes if applicable |
| Follow-up for a negative test | Z71.7 | Counseling code |
The MLN E/M booklet names HIV as an example of ongoing care that can support G2211, the visit complexity add-on, with office visits 99202 to 99215 and home visits. It is not paid when its base code carries modifier 25, except for annual wellness visits, vaccine administration and Part B preventive services.
What Does an ID Physician Need to Document for Sepsis?
Name the underlying infection and organism, and state whether any organ dysfunction was caused by the sepsis. FY 2027 guidelines section I.C.1.d codes sepsis to the underlying systemic infection, with A41.9 when the organism is not specified, and assigns R65.2 only when severe sepsis or associated organ dysfunction is documented.
Severe sepsis takes at least two codes: the infection first, then R65.20, or R65.21 with septic shock, plus a code for each acute organ dysfunction. R65.2 is never a principal diagnosis. If organ dysfunction is attributed to another condition, R65.2 is not assigned, and unclear notes are queried.
Two traps ID notes can fix: negative blood cultures do not rule out sepsis when clinical evidence exists, but the provider should be queried; and urosepsis has no default code, so write the infection and organism instead.
Can ID Follow-Up Visits Be Billed by Telehealth?
Yes. The CMS Telehealth FAQ updated October 8, 2026 says that through December 31, 2027, Medicare beneficiaries can receive telehealth services anywhere in the United States.
The CY 2026 telehealth list includes 99202 to 99205, 99212 to 99215, 99221 to 99223, 99231 to 99233 and G0316. CMS removed telehealth frequency limits on subsequent inpatient visits effective January 1, 2026. Use POS 10 for a patient at home and POS 02 elsewhere; home telehealth pays at the non-facility rate.
How Do Medicare and Commercial Payers Differ on ID Consults?
Medicare pays no consult codes, and neither does UnitedHealthcare commercial. Its policy 2026R0129A says for dates of service on or after October 1, 2019, it does not reimburse 99242 to 99245 and 99252 to 99255, including with telehealth modifiers, for any provider.
The same policy still considers telehealth consult codes G0406 to G0408, G0425 to G0427 and G0508 to G0509, and e-consults 99451, 99452 and 99446 to 99449. The requesting physician must be on the claim, in field 17B with an NPI or in field 17 by name, with a telehealth place of service.
Other commercial plans' consult policies are not covered on this page, so we read each payer's policy and contract before choosing a code. Our Medicare and UnitedHealthcare guides cover the two largest.
Does the No Surprises Act Apply to ID Physicians?
Yes, when an out-of-network ID physician treats a patient at an in-network hospital. 45 CFR 149.420(b)(1) lists services that can never use the notice and consent exception, including hospitalists, intensivists, and diagnostic and laboratory services. Infectious disease physicians are not named.
A consult may therefore qualify for notice and consent if the other conditions are met and the service did not result from unforeseen urgent medical needs (paragraph (b)(2)). Lab work billed by the same group cannot. Underpayments go to open negotiation and federal IDR, covered in our No Surprises Act pages.
How We Handle Infectious Disease Billing
We code from the note, level the visit by MDM or time, and check each claim against Medicare or the commercial policy before it leaves. Claims are sent within 24 hours of charge entry, and denials are worked within 48 hours.
To talk through your ID claims, book a call. Our medical coding and denial management teams work from your EHR.
- Medicare Claims Processing Manual, Chapter 12, sections 30.6.9, 30.6.10, 30.6.15, 30.6.18 and 180 · CMS
- MLN006764 Evaluation and Management Services, May 2026 · CMS MLN
- 2026 NCCI Medicare Policy Manual, Chapter XI · CMS
- Physician Fee Schedule relative value files, RVU26D (October 2026) · CMS
- ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 · CMS and NCHS
- Telehealth FAQ, updated 10/8/26 · CMS
- CY 2026 final list of Medicare telehealth services · CMS
- 45 CFR 149.420, non-emergency services by nonparticipating providers at participating facilities · eCFR
- Claim adjustment reason codes · X12
- Consultation Services Policy, Professional (Commercial 2026R0129A) · UnitedHealthcare
We check every rule, code and deadline against the official source. See our editorial policy.
Who We Serve




Common Questions
Straight answers from the team that does the work.
Ask a billing lead directly. A 20-minute call, Monday to Friday, 9am to 5pm Eastern.
01Which payers still accept consultation codes?
Medicare has not since January 1, 2010, and UnitedHealthcare commercial plans stopped for all providers on October 1, 2019. Other plans vary by policy and contract, and this page covers only those two. We read each remaining payer's policy first and bill the matching hospital or office E/M when consult codes are refused.
02How do we bill OPAT visits?
Bill the E/M that fits the setting, an office code from 99202 to 99215 or a home visit code from 99341 to 99350. Drug administration is billed only when your group gives the infusion in a non-facility room. Supervision of a home health patient may qualify for G0181 at 30 minutes a month.
03How do we bill infusions administered in clinic?
Report one initial administration code such as 96365 per encounter, add-on codes for further drugs, and the drug on its J-code. NCCI Chapter XI bars separate hydration, flushes and peripheral IV starts. A same-day visit takes modifier 25 only with documented separate E/M work, and never 99211.
04How do we level an inpatient ID consult?
Pick the initial hospital code, 99221 to 99223, by medical decision making or total time on the date. Medicare does not accept consult codes, so a first visit that does not meet 99221 can go out as 99231 to 99233. Document the organism, the decision and the monitoring the drug needs.
05How do we bill prolonged services?
For Medicare inpatient visits billed on time, report G0316 after 90 minutes on a 99223 or 65 minutes on a 99233, not CPT 99418, which has status I. In the office, G2212 follows 99215 at 69 to 83 minutes for one unit. Prolonged services never apply when MDM chose the level.
06How much does outsourcing Infectious Disease billing cost as a percentage of collections?
Billing is priced as a percentage of collections, and the published range appears only on our pricing page. Visit the pricing page for the range, or book a call and we will walk through what an ID group with inpatient and clinic work would need.
07Which codes should an Infectious Disease billing team know best?
The hospital pair 99223 and 99233, office visit 99214, infusion code 96365, G0316 and G2212 for time, G0181 for home care oversight, G2211 for longitudinal HIV care, and diagnoses B20, Z21, A41.9 and R65.2. Modifiers AI, FS and 25 decide whether these pay together.
08What are the most common denial reasons in Infectious Disease and how are they worked?
CO-97 for bundled infusion or same-day services, CO-4 for modifier errors, CO-18 for a second initial visit in one group, CO-16 for missing information such as the requesting physician on a telehealth consult, and CO-151 for unsupported units. We compare the 835 to the note, then fix or appeal.
09What documentation does an Infectious Disease practice need to support the codes billed?
Name the organism, the susceptibility result and the decision made, plus total time when time chose the level. On infusion days, document the separate E/M work, dose and units. For sepsis, state the infection, any organ dysfunction and whether sepsis caused it.
10How do Medicare and commercial payer rules differ for Infectious Disease claims?
Medicare pays no consult codes, uses G0316 for prolonged hospital time and requires FS on split or shared visits. UnitedHealthcare commercial policy 2026R0129A also pays no consult codes but still considers telehealth consult G-codes and e-consults when the requester is on the claim.
11Does the No Surprises Act apply to Infectious Disease claims and how are underpayments disputed?
It applies when an out-of-network ID physician treats a patient at an in-network hospital. ID is not in the ancillary list of 45 CFR 149.420(b)(1), but lab services are. Underpaid claims go to open negotiation and then federal IDR, as our No Surprises Act pages explain.
Talk to an Infectious Disease Billing Services for Id Physician Groups Billing Lead.
A 20-minute call about your payers, volume and setup. Monday to Friday, 9am to 5pm Eastern.